Chil3 ym1 chitinase-like 3
WebSimvastatin promotes Th2-type responses through the induction of the chitinase family member Ym1 in dendritic cells. Arginase-1 and Ym1 are markers for murine, but not human, alternatively activated myeloid cells. Ym1 is a neutrophil granule protein that crystallizes in p47phox-deficient mice . WebApr 10, 2024 · Chil3 chitinase-like 3 [ (house mouse)] Gene ID: 12655, updated on 10-Apr-2024. Summary. The protein encoded by this gene is similar to bacterial chitinases but …
Chil3 ym1 chitinase-like 3
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WebAug 27, 2024 · Chitinase-like protein (also named Chil3 protein or YM1) is considered a reference marker of M2 macrophage polarization (alternative activation) in mouse. 22 Our group has described a population of neutrophils, so-called N2, that expressed YM1 after rosiglitazone (PPARγ agonist) treatment in experimental ischemia. 14 Thus, we selected … WebChr3:83046658-83046795. J:101473. Microarray gene chip technology was used to identify differentially expressed candidate genes for the arthritis QTL on mouse Chromosome 3 …
Web3 Max Planck Institute for Metabolism Research, In-vivo-NMR Laboratory, Gleueler ... Fc gamma receptor III (Fcgr3) (both resembling the pro-inflammatory M1-like phenotype) or Chitinase-like 3 (Chil3/Ym1) (resembling the anti-inflammatory M2-like phenotype) promoters and stimulated transgenic cells with potent activators for pro- or anti ... WebChitinase-3-like protein 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein that is approximately 40kDa in size that in humans is encoded by the CHI3L1 gene. The name YKL-40 is derived from the three N …
WebFeb 15, 2002 · Crystals were discovered within the aged lung and at sites of chronic inflammation in a mouse model of chronic granulomatous disease. Following re-crystallization at neutral pH, the crystals were identified as the chitinase-like protein Ym1, expressed in organs of the lymphoreticular system, the lung, and distal stomach. WebChil3/YM1 is a marker protein for murine macrophages. Synthetic peptide corresponding to AA 275 to 297 from mouse Chil3. Epitop: AA 275 to 297 from mouse Chil3. Store at -20°C. Do not aliquot the antibody. Chitinase-like protein 3; Chil3; Beta-N-acetylhexosaminidase Ym1; Ym1; ECF-L; Eosinophil chemotactic cytokine.
WebNov 30, 2024 · After engagement of IL-4Rα in mice, the expression of chitinase-like protein, Ym1 (Chil3) and resistin-like molecule alpha (RELMα; Retnla) are upregulated ... Cruz Dela CS, Liu W, He CH, Jacoby A, Gornitzky A, Ma B, et al. Chitinase 3-like-1 promotes Streptococcus pneumoniae killing and augments host tolerance to lung …
WebECFC-secreted proteins were more effective in promoting NSC self-renewal than marrow stromal cell (MSC)-secreted proteins. Differential proteomics analysis of MSC-secreted and ECFC-secreted proteins was performed, which revealed chitinase-like protein 3 (CHIL3; also called ECF-L or Ym1) as a candidate niche factor for NSCs. flowers new castle indianaWebChitinase-like proteins. Mammalian CLPs have a chitin binding domain, yet lack enzymatic activity: YKL-39 (CHI3L2) and YKL-40 (CHI3L1) in humans and Ym1 (Chil3), Ym2 (Chil4) and BRP-39 (Chil1/Chi3l1) in the mouse (Table 1). In CLPs, the substitution of an essential glutamic acid to leucine, isoleucine or glutamine within the highly conserved ... flowers newfane nyWebDec 14, 2016 · In addition, pLL also inhibits IL-4-driven up-regulation of Relm-α, without similarly affecting Chitinase-like 3 (Chil3/Ym1). IL-4-driven cell proliferation and up-regulation of Relm-α are both known to depend on the phosphatidylinositol (PI3K)/Akt pathway, which is dispensable for induction of Chil3/Ym1. Exposure to pLL in vitro … green berry cluster on tree