Phospho-axl
WebPhospho-AXL (Tyr698, Tyr702, Tyr703) Antibody (BS-5181R) in IHC (P) Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-phospho-AXL … WebAXL is a receptor tyrosine kinase with a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. AXL stimulation has been described to drive cellular …
Phospho-axl
Did you know?
WebNov 12, 2024 · Axl is a receptor tyrosine kinase, which is characterized as a pro-oncogenesis factor involved in cancer progression. Along with its ligand Gas6, Axl, through its signaling, plays important physiological roles in the nervous [ 1 ], reproductive, and vascular systems [ … WebApr 12, 2024 · Human Phospho-Axl Capture Antibody (Part 841644) - Each vial contains 1440 μg/mL of mouse anti-human Axl antibody when reconstituted with 200 μL of PBS. Anti-pY-HRP A (Part 841420) - Each vial contains 50 μL of mouse anti-human phospho-tyrosine conjugated to HRP. Immediately before use, dilute the Anti-pY-HRP A in IC Diluent #14 to …
WebThe Human Phospho-Axl DuoSet IC ELISA detects ligand-induced Axl tyrosine phosphorylation. A172 cells were untreated or treated with Gas-6-containing conditioned media1 from the human lung cell line, WI38, for 15 minutes. ELISA and IP-Western blot (inset) analyses were done using 100 µg and 400 µg of lysate, respectively. WebAnti Human Phospho Axl Y779 Antibody, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
WebImmunoprecipitation of Phospho-Axl (Tyr698) protein from NCI-H1299 cells treated with GAS6 (400 ng/ml) and H 2 O 2 (4 mM) for 10 min. Lane 1 is 10% input, lane 2 is Rabbit (DA1E) mAb IgG XP ® Isotype Control #3900, lane 3 is Phospho-Axl (Tyr698)/Mer (Tyr749)/Tyro3 (Tyr681) Rabbit mAb, and lane 4 is Axl (C89E7) Rabbit mAb #8661. … WebAxl contains protein kinase activity and is activated by dimerization and auto-phosphorylation upon ligand binding. In response to its ligands, Protein S and GAS6, Axl activates anti-inflammatory pathways (through SOCS-1 and SOCS-3), which limits TLR and cytokine signaling. This results in dampened inflammatory responses in macrophages …
WebHuman Phospho-Axl Capture Antibody 841644 1 vial 2 vials Store for up to 1 month at 2-8 °C or aliquot and store at ≤ -20 °C for up to 3 months in a manual defrost freezer.* Human Phospho-Axl Control 841645 3 vials 5 vials Use within one hour of reconstitution. Use a fresh control for each assay. Anti-pY-HRP A 841420 1 vial 2 vials
WebMay 26, 2024 · This effective silencing of the phospho-AXL target thus demonstrated that aptamer specificity and bioavailability can be improved by the chemical modification of existing aptamers for phospho-AXL. These results lay the foundation for the translation of these aptamer candidates and companion biomarkers to the clinic. fitchburg wi police deptWebPhospho-Axl (Tyr702) Polyclonal Antibody (PA5-64862) Popular TaqMan Real-Time PCR Assays Antibodies Oligos, Primers & Probes GeneArt Gene Synthesis Cell Culture Plastics … fitchburg wi pdWebFormalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-phospho-AXL (Tyr698+Tyr702+Tyr703) Polyclonal Antibody, Unconjugated (bs-5181R) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Lane 1:Human A431 cell lysates; Lane 2: Human Hela cell lysates; Lane 3: Human 293T cell lysates probed … fitchburg wisconsin car insuranceWebLigand binding at the cell surface induces dimerization and autophosphorylation of AXL. Following activation by ligand, AXL binds and induces tyrosine phosphorylation of PI3-kinase subunits PIK3R1, PIK3R2 and PIK3R3; but also GRB2, PLCG1, LCK and PTPN11. Other downstream substrate candidates for AXL are CBL, NCK2, SOCS1 and TNS2. can grammarly be used offlineWebNov 1, 2024 · In humans, circulating Axl + /Siglec6 + dendritic cells and phospho-Axl + cells correlated with pulse wave velocity and aortic compliance measured by transesophageal echo, confirming chronic activation of the GAS6/Axl pathway. We conclude that brief episodes of hypertension induce chronic aortic remodeling, which is associated with … can grammarly detect plagiarismWebNov 1, 2024 · Antibodies for Western blots were as follows: antibodies to AXL (C89E7), phospho-p44/42 MAPK (Erk1/2; Thr202/Tyr204) D13.14.4E, p44/42 MAPK (Erk1/2; L34F12), phospho-Akt (Ser473; D9E), Akt (pan; 40D4) were from Cell Signaling Technology. Phospho-AXL-y779-antibody was from R&D Systems. can grammarly detect chat gptWebPhospho-AXL (Tyr698, Tyr702, Tyr703) Rabbit anti-Human Mouse Rat, Polyclonal, Bioss Rabbit Polyclonal Antibody Supplier: Bioss BS5181R Catalog No. 50-198-6392 $443.25 / Each of 1 Qty Check Availability Add to cart Description Specifications Description Axl is a member of the TAM receptor family, which also includes also MerTK and TYRO3. fitchburg wisconsin condos