Phospholipid binding protein
WebDec 22, 1998 · Anticardiolipin (aCL) autoantibodies are associated with thrombosis, recurrent fetal loss, and thrombocytopenia. Only aCL found in autoimmune disease require the participation of the phospholipid binding plasma protein β2 glycoprotein I (β2GPI) for antibody binding and now are called anti-β2GPI. WebDec 6, 2013 · Despite these varied clinical manifestations, the defining feature of this syndrome is the persistent presence of aPLs. These heterogeneous autoantibodies bind to phospholipid-binding proteins, although binding to β 2 GPI appears to identify the pathologic subgroup of antibodies that result in thrombosis and pregnancy complications. 3-5
Phospholipid binding protein
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WebThe antiphospholipid syndrome is an autoimmune disorder of hypercoagulability characterized by the presence of autoantibodies to various phospholipids or phospholipid … WebJan 23, 2008 · Phospholipids are bound to, and circulate with, positively charged phospholipid-binding proteins. Cell membranes are involved in many biological functions, …
WebJun 1, 2004 · The central biochemical characteristic of annexins is their Ca 2+ -regulated binding to the periphery of membranes containing acidic phospholipids. This could allow them to organize the interface between the cytoplasm (or cytoskeleton) and the cytoplasmic face of cellular membranes. WebNov 18, 2015 · Protein C inhibitor is a secreted, non-specific serine protease inhibitor with broad protease reactivity. It binds glycosaminoglycans and anionic phospholipids, which can modulate its activity. Anionic phospholipids, such as phosphatidylserine are normally localized to the inner leaflet of the plasma membrane, but are exposed on activated and …
WebOct 28, 2015 · The signaling cascade operating in fly photoreceptors is a G protein-coupled, phospholipase Cβ-mediated signaling pathway that is initiated by the absorption of a photon by rhodopsin and results in the opening of TRP and TRPL channels and subsequent influx of sodium and calcium ions. WebApr 2, 2024 · Phospholipid Binding of MdCAIP1 in a Ca 2+ -dependent manner. a Diagram of the predicted structure of the MdCAIP1 protein. The locations of the N and C termini and the eight β-strands in MdCAIP1 are indicated. b Amino acid sequences comparison of C2-domain in MdCAIP1 and representative C2-domain proteins in animal.
Web26 rows · Dec 8, 1998 · The aim of this review is to highlight the interplay between membrane phospholipids and cellular ...
WebDomain Binding and Function. The BAR ( B in/ A mphiphysin/ R vs) domain is found in over 35 proteins encoded in the human genome. These proteins function in diverse cellular processes such as endocytosis (i.e. endophilins, sorting nexins, and amphiphysin) and actin reorganization (i.e. RhoGAPs and RhoGEFs). The BAR domain of Arfaptin has been ... fishing pinterestWebSep 8, 2024 · A plasmid platform according to the present invention comprises a nucleic acid sequence encoding a modified protein from which an intracellular domain, an extracellular domain, or a combination thereof of lysosome-associated membrane glycoprotein 2B (LAMP-2B) has been removed, and is based on the discovery that … fishing piracyWebOct 15, 2002 · Phospholipid binding assays The binding of protein S to anionic phospholipid vesicles was assessed using a microtiter-plate assay, adapted from van Wijnen et al. 8 The washing steps were performed using buffer A. Phospholipid vesicles were coated onto the wells of microtiter plates at 25 μg/mL in 50 mM Na 2 CO 3 (pH 9.6), overnight at 4°C. fishing pirate decalsWebOct 21, 2024 · BONZAI 1 (BON1); FUNCTIONS IN: calcium-dependent phospholipid binding; INVOLVED IN: in 7 processes; LOCATED IN: plasma membrane; EXPRESSED IN: 23 plant … fishing pirate plönWebReversible interactions between acidic phospholipids in the cellular membrane and proteins in the cytosol play fundamental roles in a wide variety of physiological events. Here, we … can casual employees join kiwisaverWeb5 rows · Phospholipid binding proteins, especially β2GP1 and Annexin V, form complexes with ... George A. Fritsma, in Rodak's Hematology (Sixth Edition), 2024 Lupus … PS binding to skeletal spectrin has been shown to enhance membrane stability. … A member of complement control protein (CCP) family, β2GPI consists of 326 … fishing pin upWebDec 1, 2016 · Lipid bilayers consisting of 80 mol% phosphatidylcholine (PC) and 20 mol% phosphatidylserine (PS) have often been used as a simple model of the inner leaflet of the plasma membrane. In this system,... fishing pinwheel