WebDIM-C-pPhOH (Fig. 1C) has previously been identified as a high-affinity ligand for NR4A1 (20) (K D ;0.1 mM), and this compound induced expression of Phkg1, Pgam2, and Pygm mRNA in differentiated... WebMethods of treating endometriosis through modulation of Nuclear Receptor Subfamily 4 Group A Member 1 (NR4A1) activity including administration of an NR4A1 ligand to an individual in need thereof are described. In an embodiment, the compounds include methylene substituted diindolylmethanes.
DIM-C-pPhOH Supplier CAS 151358-47-3 Tocris …
WebApr 11, 2024 · Photo catches Taiwan pilot with a patch of Winnie the Pooh getting punched in the face — a jab at China's Xi as Beijing ups the pressure. Crew members of Taiwanese Air Force inspect an aircraft ... WebMar 14, 2024 · DIM-C-pPhOH and the 3-chloro- and 3,5-dibromo analogs did not induce all metformin-activated genes (e.g., Aldo1, Eno3, and Gpd1), but, nevertheless, there was considerable overlap in the induction of glycolytic gene expression by metformin and the C-DIM/NR4A1 ligands. DIM-C-pPhOH binds NR4A1 and acts as an NR4A1 … check status for your refund federal
PHOTO: Taiwan Pilot With Patch of Winnie the Pooh Getting …
WebApr 11, 2024 · April 11, 2024 at 5:56 a.m. EDT. Embroidered badges depict a Formosan black bear holding Taiwan’s flag and punching Winnie the Pooh. (Carlos Garcia Rawlins/Reuters) 3 min. TAIPEI, Taiwan ... WebApr 12, 2024 · Residents of Taiwan are rushing to buy a patch worn by members of its air force that mocks Chinese President Xi Jinping over his supposed resemblance to Winnie … WebDIM-C-pPhOH is a NR4A1 (Nur77) antagonist that exhibit potent anticancer activity in pancreatic, colon, breast, kidney, and rhabdomyosarcoma cells. DIM-C-pPhOH decreases expression of PAX3-FOXO1A and β1-integrin proteins in Rh30 rhabdomyosarcoma and MDA-MB-231breast cancer cells. DIM-C-pPhOH inhibits migration of Rh30 and MDA-MB-231 … check status srd grant